Geographical indications are objects of intellectual property, which serve to identify the origin of products, being guarantees of their quality and value.A new and absolutely current direction in the field of sparkling wine production is the argumentation and promotion of DOC quality, in order to increase the quality of products, expand the Grill
Background and Objectives: The mirror neuron system in the sensorimotor region of the cerebral cortex is equally activated during both action observation and execution.Action observation training mimics the functioning of the mirror neuron system, requiring patients to watch and imitate the actions necessary to perform activities of daily living.St
UCH37, also known as UCHL5, is a highly conserved Magnetic Brake Assembly deubiquitinating enzyme (DUB) that associates with the 26S proteasome.Recently, it was reported that UCH37 activity is stimulated by branched ubiquitin (Ub) chain architectures.To understand how UCH37 achieves its unique debranching specificity, we performed biochemical and N
Basil Abstract Background Ligand-binding proteins play key roles in many biological processes.Identification of protein-ligand binding residues is important in understanding the biological functions of proteins.Existing computational methods can be roughly categorized as sequence-based or 3D-structure-based methods.All these methods are based on tr
Stereotactic radiosurgery (SRS) is a special radiotherapy technique used to irradiate intracranial lesions by 3-D arrangements of narrow photon beams eliminating the needs of invasive surgery.Three different tertiary collimators, namely BrainLab and Radionics circular cones and BrainLab micro multileaf collimator (mMLC), are used for linear acceler